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As with other vaccines, the administration of Havrix should be postponed in subjects suffering from acute severe febrile illness. The presence of a minor infection, however, is not a contra-indication for vaccination.
It is possible that subjects may be in the incubation period of a hepatitis A infection at the time of vaccination. It is not known whether Havrix will prevent hepatitis A in such cases.
In haemodialysis patients and in subjects with an impaired immune system, adequate anti-HAV antibody titres may not be obtained after a single dose of Havrix and such patients may therefore require administration of additional doses of vaccine.
As with all injectable vaccines, appropriate medical treatment and supervision should always be readily available in case of a rare anaphylactic event following the administration of the vaccine.
Syncope (fainting) can occur following, or even before, any vaccination as a psychogenic response to the needle injection. It is important that procedures are in place to avoid injury from faints.
Havrix can be given to HIV-infected persons.
Seropositivity against hepatitis A is not a contra-indication.
Effects on ability to drive and use machines: The vaccine is unlikely to produce an effect on the ability to drive and use machines.
